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09/15/2004 Entry: "Drosophila Hmx gene and mouse inner ear a drama in N parts?"
biomedcentral has an interesting story -Drosophila Hmx gene directs development of mouse inner ear, an organ flies don't possess -- according to this fascinating discovery, " ... genetic mutation was not necessarily the primary evolutionary force producing morphological change in mammals ... Drosophilia Hmx gene partially rescued the development of the mouse inner ear, revealing that the gene could direct the development of an organ it does not even possess. ... Thomas Lufkin, of the Genome Institute of Singapore states "But, an equal possibility is that, instead of the gene sequence mutating, the same gene can acquire new expression domains".
Latest books on: genetic mutation:
Mutants: On Genetic Variety and the Human Body by Armand Marie Leroi
The Molecular Basis of Human Cancer by William B. Coleman
Genetics and the Search for Modern Human Origins by John H. Relethford
Systematic Approach to Evaluation of Mouse Mutations by John P. Sundberg
Directed Evolution Library Creation: Methods and Protocols (Methods in Molecular Biology, V. 231.) by Frances Hamilton Arnold
DNA Repair and Mutagenesis by Errol C. Friedberg
The Mathematical Theory of Selection, Recombination, and Mutation (Wiley Series in Mathematical & by R. Bürger
The Intelligent Genome by Adolf Heschl
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Mouse Phenotypes: A Handbook of Mutation Analysis by Virginia E Papaioannou
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